Bookmark and Share

Queen's Leads One Of The Biggest Trials In Respiratory Failure

Researchers at Queen's University Belfast are taking part in one of the biggest clinical trials in the world which could save thousands of lives in Intensive Care Units.

Queen's researchers and Belfast Health and Social Care Trust are co-leading the landmark trial involving 1,120 critically ill patients in 40 different hospital sites across the UK over the next four years.

Recruited patients will test the effectiveness of a new procedure designed to alleviate the pressure put on the lungs by mechanical ventilation.

Researchers believe the new procedure – which removes carbon dioxide from the blood in a process similar to kidney dialysis – can significantly improve survival rates in people suffering respiratory failure but only a full trial will provide evidence.
News Image
Professor Danny McAuley, Professor of Intensive Care Medicine at the Wellcome-Wolfson Institute for Experimental Medicine at Queen's said: "A mechanical ventilator acts like bellows as air is forced into the lungs under pressure. If the pressure is too high, this can cause lasting damage.

"These new devices, however, have been designed to help remove carbon dioxide from the patient's blood – in a process quite similar to kidney dialysis – which is one of the main functions of the lungs. By temporarily removing this function from the lungs, it means lungs do not have to work quite as hard, so a gentler ventilation should be sufficient.

"Recent National Institute for Health and Care Excellence (NICE) guidelines have encouraged clinicians in the UK to recruit patients to our trial which is a great endorsement of what we are doing here at Queen's."

The £2.1million research project, including the pilot trial, is being funded by the National Institute for Health Research (NIHR) Health Technology Assessment Programme.

Related Northern Ireland News Stories
Click here for the latest headlines.

01 January 2008
Social Workers Snatch Baby From Hospital
A two-hour old newborn was illegally snatched at 4am yesterday morning by social workers claiming the 18-year-old mother was unfit to care for the child because of mental health problems. But hours later a High Court judge ordered the immediate return of the baby, saying the social workers had acted beyond their powers.
24 April 2006
Man admits to Megan McAlorum murder
A man accused of murdering a Belfast teenager two years ago has admitted to the crime moments before the murder trial was due to begin. Thomas Purcell, 19, from Windsor Road, Belfast had continually denied murdering 16-year-old Megan McAlorum from Dunmurry.
17 November 2016
Sinn Féin MLA Jennifer McCann To Stand Down
Sinn Féin MLA Jennifer McCann is to stand down. She confirmed she is to take up the a new post as the party's advisor to the Health Minister. Ms McCann has been an MLA since 2007.
12 August 2016
Attempted Murder Investigation Launched Following Pipe Bomb Find
Police have launched an attempted murder investigation following the discovery of a pipe bomb in north Belfast on Tuesday, 09 August. The "viable device" was found in the North Queen Street area. Police believe it was most likely thrown at a passing PSNI vehicle the night before.
25 March 2003
UUP 'concerns' over health provision in south west
The Ulster Unionist Party has voiced its concerns over the status of health provision in Mid-Ulster, with party leader David Trimble pledging to raise the issue when the assembly gets back on track. Mr Trimble voiced his "serious concerns" over the growing gap in provision of hospital services in Tyrone.
26 January 2017
Almost 900 Patients Wait Over 12 Hours At Emergency Department's
Almost 900 patients waited more than 12 hours at hospital emergency departments in Northern Ireland in December, according to figures from the Department of Health. The patients were either waiting to be treated, discharged or admitted. A total of 62,094 people attended emergency departments, a rise of 3,360 from the previous year.
22 July 2016
Queen's Researchers To Examine How To Reverse Damage Caused By MS
Scientists at Queen's University in Belfast have started a £2 million research programme to examine how to reverse the damage caused by Multiple Sclerosis (MS). The programme is being funded by the Wellcome Trust and BBSRC.
27 September 2016
Rise In Patients Affected By Norovirus At RVH
Visitors who are experiencing symptoms of vomiting and diarrhoea by the Norovirus are being urged not to visit patients following an increase among the wards at the Royal Victoria Hospital (RVH) in Belfast.
19 July 2017
Other News In Brief
Woman Convicted Of Benefit Fraud A woman has been convicted for claiming benefits she was not entitled to at Omagh Magistrates' Court. Shauna Armstrong claimed Income Support and Carer’s Allowance totalling £3,276 while failing to declare employment. She was given a two year conditional discharge.
18 July 2017
Large Amount Of Diazepam Tablets Stolen In East Belfast
The PSNI have issued a warning after a large amount of diazepam tablets were stolen from commercial premises in east Belfast. The incident happened in the Prince Regent Road area on Monday, 17 July. A small amount of the tablets were discovered in the Orby Close area and police believe they may be linked to the burglary.
22 May 2017
Concerns Raised Over Adult Mental Health Patients
The number of adult mental health patients waiting longer than nine weeks to access key services has more than doubled from 338 in March 2016 to over 800 in March 2017, according to new figures. Ulster Unionist Mental Health spokesperson, Robbie Butler MLA, warned that mental health patients could be coming to harm.
13 December 2016
Rise In Number Of Children Calling Charity Over Transgender Fears
A charity has seen a surge in the number of children calling about gender identity issues. Childline carried out 59 counselling sessions with children from Northern Ireland who felt their biological sex did not match their gender in 2015/16.
27 October 2016
More Work Needed To Tackle Mental Health At Young Offenders Centre
More work is needed to tackle mental health issues and drug and alcohol dependency at Hydebank Wood College, a young offenders centre, according to the latest inspection.
26 January 2005
Funding secured for cystic fibrosis researchers
Cystic fibrosis researchers from Queen's University have won a share of a major £500,000 funding grant. The Cystic Fibrosis Trust was awarded £509,759 from the Big Lottery Fund to help improve the lives of disadvantaged children and young adults with the disease.
31 January 2017
PSNI Officer Awarded Queen's Gallantry Medal For Bravery
Sergeant Mark Wright has been awarded the Queen's Gallantry Medal for bravery following his action during a violent incident in Lurgan in February 2012. PSNI officers responded to a report of a man who was "dangerously out of control" at a house in the town.