17/06/2015
NI Scientists Create Dual-Acting Drug Against Diabetes
Scientists at the Ulster University have created a dual-acting drug that can help reverse the elevated body weight and blood glucose levels associated with diabetes.
The drug links an existing Type 2 Diabetes medication with a second drug that is known to reduce appetite.
Ulster University's study in diabetic mice showed that a twice daily dose over 21 days significantly lowered body weight as well as improving metabolic control.
Dr Nigel Irwin said: "When we have a meal the food we eat passes through our stomach and intestines as we slowly absorb the goodness from the food. During this process the body releases a number of important hormones from the intestines that help control appetite and blood glucose regulation. Unfortunately in Type 2 Diabetes this release of hormones does not occur correctly.
"The new drug we have developed at Ulster University aims to correct this problem by mimicking the effects of naturally occurring intestinal hormones. Our studies on mice have shown improvement in body weight and blood glucose."
(CD/MH)
The drug links an existing Type 2 Diabetes medication with a second drug that is known to reduce appetite.
Ulster University's study in diabetic mice showed that a twice daily dose over 21 days significantly lowered body weight as well as improving metabolic control.
Dr Nigel Irwin said: "When we have a meal the food we eat passes through our stomach and intestines as we slowly absorb the goodness from the food. During this process the body releases a number of important hormones from the intestines that help control appetite and blood glucose regulation. Unfortunately in Type 2 Diabetes this release of hormones does not occur correctly.
"The new drug we have developed at Ulster University aims to correct this problem by mimicking the effects of naturally occurring intestinal hormones. Our studies on mice have shown improvement in body weight and blood glucose."
(CD/MH)
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